/assets/production/practices/e626fbe66fe89e763def7d30ea6f7b65458b8e71/images/2824947.jpg)
Nausea and constipation are two of the most common digestive side effects associated with GLP-1 weight loss medications. At MetFit-Rx in Baton Rouge, Louisiana, John Fudickar, PA, and Michael Duplechain, MD, use proactive strategies to help patients stay comfortable as their bodies adapt. These include adjusted dosing, nutrition guidance, hydration support, and symptom-focused care with an individualized approach that keeps treatment safe and manageable. Call MetFit-Rx or book an appointment online today for nausea and constipation relief from GLP-1 usage.
Why do GLP-1 medications cause nausea and constipation?
Glucagon-like peptide-1 (GLP-1) medications slow digestion and help you feel full sooner, which is part of how they support weight loss. However, because food stays in the stomach longer, some patients experience nausea. At the same time, a slowed digestive system can lead to constipation.
These side effects are common, especially during the first few weeks or after the dose increases. The good news is that these symptoms usually improve as your body adjusts. The MetFit-Rx team monitors you closely during the early phase so they can step in with support before symptoms become difficult.
What can help manage nausea?
The MetFit-Rx team uses several strategies to manage nausea depending on your needs. First, they often start with microdosing or a more gradual dosing schedule to help your stomach adapt at a comfortable pace. They also encourage:
Eating smaller, more frequent meals
Prioritizing lean proteins and low-fat foods
Avoiding heavy, greasy, or sugary meals
Staying hydrated throughout the day
If nausea is more persistent, they may pause your dose increases, maintain your current dose longer, or recommend medication to ease symptoms.
What can help with constipation?
The MetFit-Rx team treats constipation proactively, with typical guidance including:
Increasing daily water intake
Eating fiber-rich foods like vegetables, berries, and whole grains
Incorporating light daily movement to stimulate digestion
Using gentle fiber supplements when needed
If these steps aren't enough, your provider may recommend stool softeners or mild over-the-counter laxatives. In some cases, they temporarily adjust your dosing schedule until your digestive system catches up.
You should reach out to MetFit-Rx if nausea becomes severe, you're unable to keep fluids down, or constipation lasts more than a few days despite following the above recommendations.
Early communication is best because a small adjustment, like holding a dose or spacing injections differently, can quickly improve your comfort.
Do nausea and constipation mean GLP-1 treatment isn't right for me?
Most patients notice at least mild nausea or changes in their bowel habits when starting GLP-1 treatment.
In most cases, patients experience improvements in side effects within weeks, especially when receiving personalized support. With the proper adjustments, most patients tolerate treatment well and continue to make steady progress toward their weight loss goals.
If you're struggling with nausea or constipation, let MetFit-Rx know because there are plenty of ways the team can help you feel better. Call the office or book an appointment online today.